Early Studies Of Male Birth-Control Pill Show Promise

By Nicole Brodeur
The Seattle Times

WWR Article Summary (tl;dr) A birth-control pill for men oral called “dimethandrolone” has been created and could be on the market in five years.

The Seattle Times

Well, well, well. The ball has been knocked roundly into your court, gentlemen.

Someday soon, you will be able to do more than just shrug on a raincoat and consider it doing your part to prevent unwanted pregnancy.

A birth-control pill for men has (finally!) been developed, and could hit the market in five years.

UW School of Medicine endocrinologist Dr. Stephanie Page presented her research recently at the Endocrine Society’s meeting in Chicago.

“My hero!” I told Page when we spoke.

“I like the sound of that,” she said.

Page studied 83 men who took the oral contraceptive, called dimethandrolone undecanoate, or DMAU, for a month, which resulted in a drop in their testosterone levels, as well as two hormones required for sperm production. There were also few side effects, and liver and kidney functions weren’t impaired.

Page made clear that this was “an early-phase study” that showed that when men took the prototype pill for a month, “We see the changes in their hormones that we think will be effective as we move along in the development.

“We haven’t proved that over 10 years it is going to be safe,” Page added. “But we are hopeful.”

Participants had a slight decrease in their HDL, or “good” cholesterol, and in a stroke of smirk-worthy karma, a slight weight gain.

This is much more acceptable than when the World Health Organization in 2016 commissioned a trial of a two-hormone injection designed to lower sperm count.

Even though the results were 96 percent effective in preventing pregnancies, the second stage of the trial was stopped after men suffered severe acne and mood swings. One man developed severe depression, and another tried to commit suicide.

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